Reduced Cortico ‐Cortical Resting‐State Connectivity in Sensory Systems Related to Bodily Pain in Juvenile Fibromyalgia

ConclusionReduced cortico-cortical sensory integration involving PCL/S1 and spanning the sensory systems may underly critical pain sensory features in youth with JFM. Reduced sensory integration is paralleled by augmented cross-talk between sensory and affective/salience-processing regions, potentially indicating a shift toward more affectively colored sensory experiences to the detriment of specific sensory discrimination.

Source: Arthritis and Rheumatology - December 21, 2023 Category: Rheumatology Authors: Maria Su ñol, Jon Dudley, Michael F. Payne, Han Tong, Tracy V. Ting, Susmita Kashikar‐Zuck, Robert C. Coghill, Marina López‐Solà Tags: Full Length Source Type: research