Feasibility and safety of sildenafil to repair brain injury secondary to birth asphyxia (SANE-01): A randomized, double-blind, placebo-controlled phase Ib clinical trial

To test feasibility and safety of administering sildenafil in neonates with neonatal encephalopathy (NE), developing brain injury despite therapeutic hypothermia (TH).

Source: The Journal of Pediatrics - December 21, 2023 Category: Pediatrics Authors: Pia Wintermark, Anie Lapointe, Robin Steinhorn, Emmanouil Rampakakis, J ürgen Burhenne, Andreas D. Meid, Gzona Bajraktari-Sylejmani, May Khairy, Gabriel Altit, Marie-Therese Adamo, Alishia Poccia, Guillaume Gilbert, Christine Saint-Martin, Daniela Toffol Tags: Original Articles Source Type: research