New portable PET scanner tested in humans

In this study, they aimed to establish the feasibility of the approach using an experimental scanner called CerePET (Brain Biosciences, Rockville, MD).Each of the 20 healthy volunteers underwent dynamic F-18 FDG imaging with both scanners one to 154 days apart. Standard radiotracer uptake values (SUV) in brain tissue and rates of glucose metabolism (CMRglu) were quantified and compared between the scanners at regional and voxel levels.According to the findings, outcome measures were well correlated, the group wrote. Specifically, correlation coefficients between the imaging sets across participants were 0.83 ± 0.07 for SUV and 0.85 ± 0.08 for CMRglu, the researchers reported.“Our results indicate robust correlation and agreement between semi- and fully quantitative brain glucose metabolism measurements from portable CerePET and standard Biograph mCT scanners,” the group wrote.Ultimately, at this stage, the major finding is that there appears to be no significant differences in fully quantified dynamic outcomes in cortical and subcortical brain areas between the two scanners indicating that the CerePET scanner is ready for imaging human subjects, they wrote.“Future work will focus on more detailed scanner performance characterization, followed by application of CerePET to novel PET scanning scenarios,” the group concluded. A link to the full study can be found here.
Source: AuntMinnie.com Headlines - Category: Radiology Authors: Tags: Molecular Imaging Source Type: news