Association Between Altered White Matter Networks and Post Operative Ventricle Volume in Shunt-Treated Pediatric Hydrocephalus

CONCLUSIONS: This cross-sectional study in pediatric patients with hydrocephalus and healthy controls demonstrated using whole-brain probabilistic tractography that there are various networks with dysregulated white matter integrity in hydrocephalus patients relative to controls. These dysregulated networks have tracts connecting structures throughout the brain, and the regions were predominately located centrally and posteriorly. Post-operative ventricle volume did not predict the white matter integrity of many tracts. Future studies with larger sample sizes are needed to further understand these results.PMID:38103800 | DOI:10.1016/j.brainresbull.2023.110847
Source: Brain Research Bulletin - Category: Neurology Authors: Source Type: research