Performance evaluation of core genome multilocus sequence typing for genotyping of Mycobacterium tuberculosis strains in China: based on multicenter, population-based collection

Conclusion  cgMLST showed a discriminatory power comparable to whole-genome SNP typing and could be used to genotype clinicalM.tuberculosis strains in different regions of China. The discriminative power of cgMLST was significantly correlated with strain genetic diversity and was slightly lower with strains from regions with low genetic diversity.
Source: European Journal of Clinical Microbiology and Infectious Diseases - Category: Microbiology Source Type: research