AMPK-HIF-1 α signaling enhances glucose-derived de novo serine biosynthesis to promote glioblastoma growth

Cancer cells undergo cellular adaptation through metabolic reprogramming to sustain survival and rapid growth under various stress conditions. However, how brain tumors modulate their metabolic flexibility in ...

Source: Journal of Experimental and Clinical Cancer Research - December 15, 2023 Category: Cancer & Oncology Authors: Hye Jin Yun, Min Li, Dong Guo, So Mi Jeon, Su Hwan Park, Je Sun Lim, Su Bin Lee, Rui Liu, Linyong Du, Seok-Ho Kim, Tae Hwan Shin, Seong-il Eyun, Yun-Yong Park, Zhimin Lu and Jong-Ho Lee Tags: Research Source Type: research