Fiber-deficient diets reprogram the microbiota

Cell Host Microbe. 2023 Dec 13;31(12):1950-1951. doi: 10.1016/j.chom.2023.11.014.ABSTRACTExclusive enteral nutrition, a diet lacking fiber, is used to treat pediatric Crohn's disease. In this issue of Cell Host & Microbe, Kuffa et al. find that a fiber-deficient diet thins the mucus layer and alters microbial cross-feeding, causing pro-inflammatory Mucispirillum to move away from the epithelium, which ameliorates colitis.PMID:38096786 | DOI:10.1016/j.chom.2023.11.014

Source: Cell Host and Microbe - December 14, 2023 Category: Microbiology Authors: Bradley G Fitzgerald Matthew T Sorbara Source Type: research