Development of a molecular barcode detection system for pancreaticobiliary malignancies and comparison with next-generation sequencing

Pancreatic cancer (PC) is the fourth leading cause of cancer-related death in Western countries and expected to become the second-leading cause of cancer-related deaths in the United States by 2030.[1,2] The 5-year survival rate for all combined stages (9%) of PC is the lowest of all cancer types.[2] The incidence of biliary tract cancer (BTC), including intrahepatic and extrahepatic cholangiocarcinoma (CCA) and gallbladder cancer (GBC), remains highest in East Asia and parts of South America and is rapidly increasing worldwide.

Source: Cancer Genetics and Cytogenetics - December 13, 2023 Category: Genetics & Stem Cells Authors: Hiroshi Ohyama, Yosuke Hirotsu, Kenji Amemiya, Rintaro Mikata, Hiroyuki Amano, Sumio Hirose, Toshio Oyama, Yuji Iimuro, Yuichiro Kojima, Hitoshi Mochizuki, Naoya Kato, Masao Omata Source Type: research