Interferon lambda receptor-1 isoforms differentially influence gene expression and HBV replication in stem cell-derived hepatocytes

CONCLUSIONS: IFNLR1 isoforms differentially influence IFNL-induced gene expression and HBV replication in hepatocytes. Regulated IFNLR1 expression in vivo could limit the capacity of this pathway to counteract HBV replication.PMID:38070830 | DOI:10.1016/j.antiviral.2023.105779

Source: Antiviral Research - December 9, 2023 Category: Virology Authors: Laura A Novotny J Grayson Evans Haitao Guo Christiana S Kappler Eric G Meissner Source Type: research