Childhood asthma clusters and response to therapy in clinical trials

Conclusions: In this study, we replicated SARP pediatric asthma clusters by using a separate, large clinical trials network. Early-onset/severe-lung function and early-onset/comorbidity clusters were associated with differential and limited response to therapy, respectively. Further prospective study of therapeutic response by cluster could provide new insights into childhood asthma treatment.
Source: Journal of Allergy and Clinical Immunology - Category: Allergy & Immunology Authors: Tags: Asthma and lower airway disease Source Type: research