Erastin induces ferroptosis in cervical cancer cells via Nrf2/HO-1 signaling pathway

CONCLUSION: Our research demonstrates that erastin induces ferroptosis and the accumulation of ROS in cervical cancer cells by activating the Nrf2/HO-1 pathway, significantly reducing cell proliferation and motility. These findings propose a potential molecular mechanism of erastin-mediated cervical cancer development.PMID:38031977 | PMC:PMC10687934 | DOI:10.1177/03946320231219348

Source: International Journal of Immunopathology and Pharmacology - November 30, 2023 Category: Allergy & Immunology Authors: Xiaoning Wei Qiaoqiao Huang Jinbing Huang Li Yu Junying Chen Source Type: research