Leonurine ameliorates the STAT3 pathway through the upregulation of SHP-1 to retard the growth of hepatocellular carcinoma cells

In conclusion, Leo was demonstrated to induce cytotoxicity in HCC cells by mitigating the persistent of activation of STAT3 pathway.PMID:38048857 | DOI:10.1016/j.cellsig.2023.111003

Source: Cellular Signalling - December 4, 2023 Category: Cytology Authors: Young Yun Jung Chulwon Kim Muthu K Shanmugam Amudha Deivasigamani Arunachalam Chinnathambi Sulaiman Ali Alharbi Kanchugarakoppal S Rangappa Kam Man Hui Gautam Sethi Chakrabhavi Dhananjaya Mohan Kwang Seok Ahn Source Type: research