Computational Approaches: A New Frontier in Cancer Research

Comb Chem High Throughput Screen. 2023 Nov 28. doi: 10.2174/0113862073265604231106112203. Online ahead of print.ABSTRACTCancer is a broad category of disease that can start in virtually any organ or tissue of the body when aberrant cells assault surrounding organs and proliferate uncontrollably. According to the most recent statistics, cancer will be the cause of 10 million deaths worldwide in 2020, accounting for one death out of every six worldwide. The typical approach used in anti-cancer research is highly time-consuming and expensive, and the outcomes are not particularly encouraging. Computational techniques have been employed in anti-cancer research to advance our understanding. Recent years have seen a significant and exceptional impact on anticancer research due to the rapid development of computational tools for novel drug discovery, drug design, genetic studies, genome characterization, cancer imaging and detection, radiotherapy, cancer metabolomics, and novel therapeutic approaches. In this paper, we examined the various subfields of contemporary computational techniques, including molecular docking, artificial intelligence, bioinformatics, virtual screening, and QSAR, and their applications in the study of cancer.PMID:38031782 | DOI:10.2174/0113862073265604231106112203
Source: Combinatorial Chemistry and High Throughput Screening - Category: Chemistry Authors: Source Type: research