Expression of Nectin-4 in Chromophobe Renal Cell Carcinoma in a multicenter cohort - early prognostic and therapeutic considerations

CONCLUSIONS: In chRCC a small subset of tumors expresses Nectin-4 potentially amenable to Nectin-4 directed treatment. Expression of Nectin-4 is not associated with parameters of aggressiveness or survival. Due to the rare incidence of chRCC further studies with larger cohorts are warranted.PMID:38043528 | DOI:10.1159/000535473

Source: Oncology - December 3, 2023 Category: Cancer & Oncology Authors: Marie Mikuteit Stefanie Zsch äbitz Michael Autenrieth Wilko Weichert Arndt Hartmann Sandra Steffens Franziska Erlmeier Source Type: research