Pilot Study of High-Dose Pemetrexed in Patients with Progressive Chordoma

CONCLUSIONS: High-dose pemetrexed appears tolerable and shows objective antitumor activity in patients with chordoma. Phase II studies of high-dose pemetrexed are warranted.PMID:38047868 | DOI:10.1158/1078-0432.CCR-23-2317

Source: Clinical Cancer Research - December 4, 2023 Category: Cancer & Oncology Authors: Santosh Kesari Naveed Wagle Jose A Carrillo Akanksha Sharma Minhdan Nguyen Judy Truong Jaya M Gill Raffi Nersesian Natsuko Nomura Elnaz Rahbarlayegh Garni Barkhoudarian Walavan Sivakumar Daniel F Kelly Howard Krauss Matias A Bustos Dave S B Hoon Lars Anke Source Type: research