Abelson Helper Integration Site 1 haplotypes and peripheral blood expression associates with lithium response and immunomodulation in bipolar patients

ConclusionsOur study suggests the involvement ofAHI1 in the lithium mode of action. Moreover, mood-stabilizing treatment associated with the innate immunity-related gene expression in BD patients and only the lithium-treated BD patients showed significantly elevated expression of anti-inflammatoryIL10, suggesting lithium ’s immunomodulatory potential.
Source: Psychopharmacology - Category: Psychiatry Source Type: research