Cancers, Vol. 15, Pages 5661: Chimeric Antigen Receptor-T Cell and Oncolytic Viral Therapies for Gastric Cancer and Peritoneal Carcinomatosis of Gastric Origin: Path to Improving Combination Strategies

In this study, we provide an up-to-date review of the pre-clinical and clinical efficacy of CAR T cell therapy for key primary antigen targets and provide a translational overview of the types, modifications, and mechanisms for OVs used against GC and GCPC. Finally, we present a novel, summary-based discussion on the potential synergistic interplay between OVs and CAR T cells to treat GCPC.

Source: Cancers - November 30, 2023 Category: Cancer & Oncology Authors: Courtney Chen Audrey Jung Annie Yang Isabel Monroy Zhifang Zhang Shyambabu Chaurasiya Supriya Deshpande Saul Priceman Yuman Fong Anthony K. Park Yanghee Woo Tags: Review Source Type: research