The cyclin-dependent kinase inhibitor abemaciclib-induced hepatotoxicity: insight on the molecular mechanisms in HepG2/THP-1 co-culture model

In conclusion; the study makes a significant contribution to strengthening the infrastructure we have on in vitro toxicity mechanism evaluations, which are the basis of preclinical toxicity studies.PMID:37992977 | DOI:10.1016/j.toxlet.2023.11.005

Source: Toxicology Letters - November 22, 2023 Category: Toxicology Authors: Tugce Boran Ozge Sultan Zengin Zehra Seker Aysenur Gunaydin Akyildiz Ezgi Oztas G ül Özhan Source Type: research