An environmentally benign protocol for the synthesis of sugar 1,2-orthoesters in poly(ethylene glycol) dimethyl ether (DMPE)

Carbohydr Res. 2023 Jul 20;534:108902. doi: 10.1016/j.carres.2023.108902. Online ahead of print.ABSTRACTAn environmentally benign procedure has been developed for the synthesis of sugar orthoesters using anhydrous sodium acetate in poly (ethylene glycol)dimethyl ether (DMPE). Various sugar orthoesers were prepared without using volatile organic solvent and quaternary ammonium salt. The sugar orthoesters were obtained in good to excellent yields.PMID:38006705 | DOI:10.1016/j.carres.2023.108902
Source: Carbohydrate Research - Category: Genetics & Stem Cells Authors: Source Type: research