Genetically Regulated Gene Expression in the Brain Associated With Chronic Pain: Relationships With Clinical Traits and Potential for Drug Repurposing

Chronic pain is a common, poorly understood condition. Genetic studies including genome-wide association studies have identified many relevant variants, which have yet to be translated into full understanding of chronic pain. Transcriptome-wide association studies using transcriptomic imputation methods such as S-PrediXcan can help bridge this genotype-phenotype gap.

Source: Biological Psychiatry - September 5, 2023 Category: Psychiatry Authors: Keira J.A. Johnston, Alanna C. Cote, Emily Hicks, Jessica Johnson, Laura M. Huckins Tags: Archival Report Source Type: research