Rivaroxaban, a factor Xa inhibitor, improves neovascularization in the ischemic hindlimb of streptozotocin-induced diabetic mice
Conclusions:
Rivaroxaban promoted vessel formation in diabetic mice and improved endothelial progenitor cell function under hyperglycemic conditions. These effects may be associated with enhancement of expression of eNOS and VEGF.
Source: Cardiovascular Diabetology - Category: Cardiology Authors: Tao-Cheng WuJenq-Shyong ChanChiu-Yang LeeHsin-Bang LeuPo-Hsun HuangJia-Shiong ChenShing-Jong LinJaw-Wen Chen Source Type: research
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