Nosocomial pneumonia: Current etiology and impact on antimicrobial therapy

Rev Esp Quimioter. 2023 Nov;36 Suppl 1:9-14. doi: 10.37201/req/s01.03.2023. Epub 2023 Nov 24.ABSTRACTNosocomial pneumonia is an infection with high clinical impact and high morbimortality in which Pseudomonas aeruginosa plays a priority role, especially in the critically ill patient. Conventional antipseudomonal treatments, historically considered as standard, are currently facing important challenges due to the increase of antimicrobial resistance. In recent years, new antimicrobials have been developed with attractive sensitivity profiles and remarkable efficacy in clinical scenarios of nosocomial pneumonia including bacteremia, mechanical ventilation, infections with multidrug-resistant organisms or situations of therapeutic failure. This new evidence underscores the need to update current clinical guidelines for the antimicrobial treatment of nosocomial pneumonia, especially in the most critically ill patients.PMID:37997863 | DOI:10.37201/req/s01.03.2023

Source: Revista Espanola de Quimioterapia - November 24, 2023 Category: Drugs & Pharmacology Authors: J J Gamazo F J Candel J Gonz ález Del Castillo Source Type: research