Lung transcriptomics of K18-hACE2 mice highlights mechanisms and genes involved in the MVA-S vaccine-mediated immune response and protection against SARS-CoV-2 infection

This study shows host transcriptomic mechanisms likely involved in the MVA-S vaccine-mediated immune response against SARS-CoV-2 infection, which could help in improving vaccine dose assessment and developing novel, well-optimized SARS-CoV-2 vaccine candidates against prevalent or emerging VoCs.PMID:37992765 | DOI:10.1016/j.antiviral.2023.105760

Source: Antiviral Research - November 22, 2023 Category: Virology Authors: Alberto G ómez-Carballa Guillermo Albericio Juli án Montoto-Louzao Patricia P érez David Astorgano Irene Rivero-Calle Federico Martin ón-Torres Mariano Esteban Antonio Salas Juan Garc ía-Arriaza Source Type: research