Polygenic risk scores for Alzheimer's disease in relation to cognitive change: A representative sample from the general population followed over 16  years

CONCLUSION: We found that genetic predisposition of AD predicted cognitive decline among 70-year-olds followed over 16 years, regardless of dementia status, while polygenic risk for general cognitive performance did not.PMID:37977433 | DOI:10.1016/j.nbd.2023.106357

Source: Neurobiology of Disease - November 17, 2023 Category: Neurology Authors: Jenna Najar Valgeir Thorvaldsson Silke Kern Johan Skoog Margda Waern Henrik Zetterberg Kaj Blennow Ingmar Skoog Anna Zettergren Source Type: research