Burden of diarrhea and antibiotic use among children in low-resource settings preventable by < i > Shigella < /i > vaccination: A simulation study

ConclusionsOur simulation results suggest that aShigella vaccine meeting WHO targets for efficacy could prevent about a third ofShigella diarrhea episodes, antibiotic use to treat shigellosis, and bystander exposures due to shigellosis treatment. However, the reductions in overall diarrhea episodes and antibiotic use are expected to be modest (
Source: PLoS Medicine - Category: Internal Medicine Authors: Source Type: research