Telomere shortening induces aging-associated phenotypes in hiPSC-derived neurons and astrocytes

This study serves as a proof of concept that telomere shortening can effectively induce aging-associated phenotypes, thereby providing a valuable tool to investigate age-related decline and neurodegenerative diseases.PMID:37987889 | DOI:10.1007/s10522-023-10076-5

Source: Biogerontology - November 21, 2023 Category: Geriatrics Authors: Jasmine Harley Munirah Mohamad Santosa Chong Yi Ng Oleg V Grinchuk Jin-Hui Hor Yajing Liang Valerie Jingwen Lim Wee Wei Tee Derrick Sek Tong Ong Shi-Yan Ng Source Type: research