Pharmacokinetics and therapeutic target attainment of vancomycin in pediatric post-liver transplant patients

CONCLUSIONS: Pediatric patients with preserved renal function after liver transplantation have an increased volume of distribution for vancomycin, and most patients present subtherapeutic levels after the standard initial dosing regimen. With the vancomycin AUC-guided monitoring and dosing, it is possible to improve therapeutic target attainment.PMID:37977199 | DOI:10.1016/j.bjid.2023.103688

Source: Braz J Infect Dis - November 17, 2023 Category: Infectious Diseases Authors: Ronaldo Morales Vanessa D'Amaro Juodinis Daniela Carla de Souza Silvia Regina Cavani Jorge Santos Source Type: research