Cerebral Metabolic Signature of Chronic Benzodiazepine Use in Nondemented Older Adults: An FDG-PET Study in the MEMENTO Cohort

CONCLUSION: Our study is the first to find a greater global metabolism in chronic BZD users and a specific greater metabolism in the right amygdala. Because the acute administration of BZDs tends to reduce brain metabolism, these findings may correspond to a compensatory mechanism while the brain adapts with global metabolism upregulation, with a specific focus on the right amygdala.PMID:37973486 | DOI:10.1016/j.jagp.2023.10.002

Source: Am J Geriatr Psychia... - November 16, 2023 Category: Geriatrics Authors: Quentin Gallet Vincent Bouteloup Maxime Locatelli Marie-Odile Habert Marie Chupin Jacques-Yves Campion Pierre-Emmanuel Michels Julien Delrieu Thibaud Lebouvier Anna-Chlo é Balageas Alexandre Surget Catherine Belzung Nicolas Arlicot Maria-Joao Santiago Ri Source Type: research