Nutrimetric validation of solanidine as dietary-derived CYP2D6 activity marker in vivo

This study substantiates the MR SSDA/solanidine as CYP2D6 activity marker. The high correlation with metoprolol MR indicates a valid prediction of the CYP2D6 phenotype at any time point during the study day.PMID:37971251 | DOI:10.1002/cpt.3106

Source: Clinical Pharmacology and Therapeutics - November 16, 2023 Category: Drugs & Pharmacology Authors: Julian Peter M üller Jens Sar ömba Patrick Ziegler Roman Tremmel Jens Rengelshausen Elke Schaeffeler Katja S Just Matthias Schwab Thomas Kraus Julia C Stingl Source Type: research