Proteomic and metabolomic characterizations of moyamoya disease patient sera

ConclusionsSignificant increases in pro-inflammatory and immunosuppressive abilities have been observed in patients with MMD, accompanied by significant reductions in anti-inflammatory and immune regulation. Various metabolites and proteins implicated in these processes have been identified for the first time. These findings hold immense significance for comprehending the pathogenesis of MMD and for the development of future drug therapies.

Source: Brain and Behavior - November 14, 2023 Category: Neurology Authors: Qingbao Guo, Qian ‐Nan Wang, Jingjie Li, Simeng Liu, Xiaopeng Wang, Dan Yu, Zheng‐Xing Zou, Gan Gao, Qian Zhang, Fang‐Bin Hao, Jie Feng, Ri‐Miao Yang, Minjie Wang, Heguan Fu, Xiangyang Bao, Lian Duan Tags: ORIGINAL ARTICLE Source Type: research