Distinct Effects of Non-absorbed Agents Rifaximin and Berberine on the Microbiota-Gut-Brain Axis in Dysbiosis-induced Visceral Hypersensitivity in Rats

CONCLUSIONS: Berberine enriched Lachnoclostridium, reduced the expression of peptidoglycan biosynthesis genes and increased acetate and propionate. The absence of these actions of rifaximin may explain the different effects of the drugs on microbiota-gut-brain axis.PMID:37814439 | PMC:PMC10577460 | DOI:10.5056/jnm22182

Source: Journal of Neurogastroenterology and Motility - October 10, 2023 Category: Gastroenterology Authors: Jindong Zhang Cunzheng Zhang Tao Zhang Lu Zhang Liping Duan Source Type: research