Daily methocinnamox treatment dose-dependently attenuates fentanyl self-administration in rhesus monkeys

This study demonstrates that MCAM reliably and dose-dependently decreases fentanyl self-administration and prevents opioid overdose, with no evidence of any adverse effects over a broad dose range, further supporting the potential therapeutic utility of this novel antagonist.PMID:37944894 | DOI:10.1016/j.neuropharm.2023.109777

Source: Neuropharmacology - November 9, 2023 Category: Drugs & Pharmacology Authors: David R Maguire Charles P France Source Type: research