The inferior performance of [ < sup > 68 < /sup > Ga]Ga-FAPI-04 PET/CT as a diagnostic and theranostic biomarker in [ < sup > 177 < /sup > Lu]Lu-DOTATATE refractory well-differentiated neuroendocrine tumors

CONCLUSION: Our preliminary results demonstrated that [68Ga]Ga-FAPI-04 PET/CT mainly failed in well-differentiated NETs refractory to [177Lu]Lu-DOTATATE therapy and had a limited role as an alternative diagnostic or theranostic agent. Further investigations with a larger patient population are required to determine the impact of [68Ga]Ga-FAPI-04 PET/CT on NETs.PMID:37947850 | DOI:10.1007/s00259-023-06497-6

Source: Molecular Medicine - November 10, 2023 Category: Molecular Biology Authors: Duygu Has Simsek Yunus Guzel Dilara Denizmen Yasemin Sanli Fikret Buyukkaya Bilal Kovan Halil Komek Emine Goknur Isik Zeynep Gozde Ozkan Serkan Kuyumcu Source Type: research