Season of radiotherapy and outcomes of head & neck cancer patients in the MACH-NC & MARCH meta-analyses

Head and neck squamous cell cancer (HNSCC) accounts for approximately 800,000 cases and 400,000 deaths annually worldwide [1]. The standard of care for locally-advanced disease for oral cavity, oropharynx, hypopharynx, and larynx subsites is a multimodality treatment with permutations of radiation therapy (RT), chemotherapy (CT), and surgery, in function of tumor localization. Treatment sequelae in these highly functional zones may significantly affect quality of life; and despite optimal treatment, mortality remains high.

Source: Radiotherapy and Oncology - November 10, 2023 Category: Radiology Authors: Elaine LIMKIN, Pierre BLANCHARD, Benjamin LACAS, Jean BOURHIS, Mahesh PARMAR, Lisa LICITRA, Quynh-Thu LE, Sue YOM, Catherine FORTPIED, Johannes LANGENDIJK, Jan B VERMORKEN, Jacques BERNIER, Jens OVERGAARD, Jonathan HARRIS, Jean-Pierre PIGNON, Anne AUPERIN Tags: Original Article Source Type: research