Identification of hub biomarkers and immune-related pathways participating in the progression of Kawasaki disease by integrated bioinformatics analysis

CONCLUSION: Activated dendritic cells, neutrophils, and macrophages were closely associated with the pathogenesis of KD. Furthermore, the hub genes (S100A12, MMP9, TLR2, NLRC4, and ARG1) are likely to participate in the pathogenic mechanisms of KD through immune-related signaling pathways.PMID:37837870 | DOI:10.1016/j.imbio.2023.152750

Source: Immunobiology - October 14, 2023 Category: Allergy & Immunology Authors: Yang Gao Xuan Tang Guanghui Qian Hongbiao Huang Nana Wang Yan Wang Wenyu Zhuo Jiaqi Jiang Yiming Zheng Wenjie Li Zhiheng Liu Xuan Li Lei Xu Jiaying Zhang Li Huang Ying Liu Haitao Lv Source Type: research