Understanding nucleic acid sensing and its therapeutic applications

Experimental & Molecular Medicine, Published online: 09 November 2023; doi:10.1038/s12276-023-01118-6The study highlights the role of nucleic acid sensors in recognizing and destroying microbes, and their potential as targets for cancer therapy and autoimmune disease treatment. Researchers found that modifying these sensors can improve the efficiency of mRNA vaccines and reduce their immunogenicity. Additionally, understanding the crosstalk between different nucleic acid sensing pathways can help develop new optimization strategies for cancer immunotherapy. These findings pave the way for novel therapeutic approaches that harness the power of the immune system to combat various diseases.This summary was initially drafted using artificial intelligence, then revised and fact-checked by the author.
Source: Experimental and Molecular Medicine - Category: Molecular Biology Authors: Source Type: research