Sarcoid optic neuropathy

Pract Neurol. 2023 Nov 6:pn-2023-003939. doi: 10.1136/pn-2023-003939. Online ahead of print.ABSTRACTA 45-year-old woman presented with sudden complete vision loss in her left eye and retroorbital pain worsened by eye movements. A previous milder episode of vision loss had occurred in the same eye 1 year before, with complete recovery after high-dose intravenous methylprednisolone. She had no light perception in the left eye with a swollen optic disc, but with a normal right optic disc. There were no systemic manifestations or infections. MR scan of the brain showed extensive enlargement and enhancement of the left optic nerve and optic chiasm. After excluding infections and autoimmune markers, a left optic nerve biopsy confirmed non-caseating granulomas, leading to a diagnosis of neurosarcoidosis.PMID:37932041 | DOI:10.1136/pn-2023-003939

Source: Practical Neurology - November 6, 2023 Category: Neurology Authors: Pedro Fraiman Andr é Lopes Valente Maria Eduarda Slhsessarenko Fraife Barreto Nath ália Lopes Silva Flavio Moura Rezende Filho Vin ícius Lopes Braga Marianna Pinheiro Moraes Jos é Luiz Pedroso Orlando G P Barsottini Source Type: research