mTOR eosinophilic renal cell carcinoma: a distinctive tumor characterized by mTOR mutation, loss of chromosome 1, cathepsin-K expression, and response to target therapy

We present a distinct renal tumor characterized by high-grade eosinophilic cells, cathepsin-K immunohistochemical expression, and harboringmTOR gene mutations demonstrating a malignant potential and showing responsiveness to mTOR inhibitors.
Source: Virchows Archiv - Category: Pathology Source Type: research