Hitting the Target: Developing High-quality Evidence for Proton Beam Therapy Through Randomised Controlled Trials

We present a summary of three UK PBT RCTs in progress, including consideration of their key design characteristics and outcome assessments, to inform and support future PBT trial development. The first three UK multicentre phase III PBT RCTs (TORPEdO, PARABLE and APPROACH), will compare PBT with photon radiotherapy for oropharyngeal squamous cell carcinoma, breast cancer and oligodendroglioma, respectively.

Source: Clinical Oncology - November 8, 2023 Category: Radiology Authors: E.M. Hudson, F. Slevin, K. Biscombe, S.R. Brown, J.S. Haviland, L. Murray, A.M. Kirby, D.J. Thomson, D. Sebag-Montefiore, E. Hall Tags: Overview Source Type: research