RNA-seq analysis reveals prenatal alcohol exposure is associated with placental inflammatory cells and gene expression

CONCLUSIONS: Our findings suggest that heavy alcohol exposure during pregnancy can influence the proportion of fetal placental villi macrophages (Hofbauer cells) and increased expression of inflammatory genes. Future studies are needed to further characterize these effects and to assess the potential functional roles of placental inflammation in FASD.PMID:37918548 | DOI:10.1016/j.gene.2023.147951

Source: Gene - November 2, 2023 Category: Genetics & Stem Cells Authors: Randy P Williams Corina Lesseur Haoxiang Cheng Qian Li Maya Deyssenroth Christopher D Molteno Ernesta M Meintjes Sandra W Jacobson Joseph L Jacobson Helen Wainwright Ke Hao Jia Chen R Colin Carter Source Type: research