Salvianolic acid B exerts protective effects against A β-induced neuroinflammation through the inhibition of NLRP3 inflammasome activation and switching of M1/M2 polarization

CONCLUSION: our study demonstrated, for the first time, that the anti-inflammatory effects of SalB were mediated by the regulation of NLRP3 activation and promotion of microglial M2 polarization, indicating the potential of SalB as a novel therapeutic candidate for AD.PMID:37913602 | DOI:10.1016/j.tice.2023.102260

Source: Tissue and Cell - November 1, 2023 Category: Cytology Authors: Yuan Zhao Xin Liu Xiang Liu Jian Zhang Yidan Zhang Ya Wen Guofeng Yang Source Type: research