Sensitization to Staphylococcus aureus toxins in Severe Asthma. The Belgian IgE (BEIgE) study.

Conclusion: Patients with SA and StA-monosensitization display a ‘Type 2’ (T2) airways inflammatory profile and may therefore represent a T2 SA subgroup which is incorrectly considered as ‘non-sensitized’; testing for StA toxins may therefore be indicated in this group of patients. Further prospective studies are needed to establish whether they might benefit from anti-IgE therapy.

Source: European Respiratory Journal - October 27, 2023 Category: Respiratory Medicine Authors: Schleich, F., Maury, E., Bachert, C., Jansen, M., Gurdain, S., Van Schoor, J. Tags: Allergy and immunology Source Type: research