Cognitive dysfunction in pediatric systemic lupus erythematosus: current knowledge and future directions

Child Neuropsychol. 2023 Oct 30:1-29. doi: 10.1080/09297049.2023.2273573. Online ahead of print.ABSTRACTCognitive dysfunction (CD) is a neurologic complication of pediatric systemic lupus erythematosus (SLE) that remains poorly understood and understudied, despite the potential negative effects of CD on long-term socioeconomic status and quality of life. Data regarding the prevalence and risk factors for CD in pediatric SLE as well as the optimal screening, treatment, and long-term outcomes for CD are lacking. In this review, we present current knowledge on CD in pediatric SLE with a focus on the application to clinical practice. We discuss the challenges in diagnosis, clinical screening methods, potential impacts, and interventions for this complication. Finally, we discuss the remaining gaps in our knowledge of CD in pediatric SLE, and avenues for future research efforts.PMID:37902575 | DOI:10.1080/09297049.2023.2273573
Source: Child Neuropsychology - Category: Child Development Authors: Source Type: research