Multi-tissue epigenetic analysis identifies distinct associations underlying insulin resistance and Alzheimer ’s disease at CPT1A locus

Insulin resistance (IR) is a major risk factor for Alzheimer ’s disease (AD) dementia. The mechanisms by which IR predisposes to AD are not well-understood. Epigenetic studies may help identify molecular signat...

Source: Clinical Epigenetics - October 27, 2023 Category: Research Authors: Chlo é Sarnowski, Tianxiao Huan, Yiyi Ma, Roby Joehanes, Alexa Beiser, Charles S. DeCarli, Nancy L. Heard-Costa, Daniel Levy, Honghuang Lin, Ching-Ti Liu, Chunyu Liu, James B. Meigs, Claudia L. Satizabal, Jose C. Florez, Marie-France Hivert, Josée Dupui Tags: Research Source Type: research