Diagnostic accuracy of virtual non-contrast CT for aortic valve stenosis severity evaluation

We studied 109 prospectively included patients undergoing multi-energy CT (MECT) for transcatheter aortic valve replacement (TAVR). True non-contrast (TNC)- aortic valve calcium (AVC) score was prospectively acquired and virtual non-contrast (VNC)-AVC score derived from a contrast-enhanced scan. Agatston method was used and a correction proportionality constant was applied to VNC values. A total of 43% had concordant severe and 14% concordant moderate aortic stenosis (AS). MECT-derived VNC-AVC showed a strong correlation with TNC-AVC. After adjustment, VNC-AVC demonstrated substantial agreement with TNC-AVC, potentially eliminating the requirement for an additional scan and enabling reductions in both radiation exposure and acquisition time.

Source: Journal of Cardiovascular Computed Tomography - October 28, 2023 Category: Radiology Authors: Daniel Lorenzatti, Pamela Pi ña, Jonathan Daich, Andrea Scotti, Javier Perez-Cervera, Rita Miranda, Ari J. Feinberg, Sandra S. Halliburton, Thomas B. Ivanc, Aldo L. Schenone, Toshiki Kuno, Azeem Latib, Damini Dey, Philippe Pibarot, Marc R. Dweck, Mario J Tags: Research paper Source Type: research