Province-Wide Ascertainment of Lynch Syndrome in Manitoba

CONCLUSIONS: A tumour screening program is more effective at detecting individuals with lower penetrant gene variants and families who do not meet traditional family history-based criteria. Cascade genetic testing is higher among clinic referrals compared to the screening program. These findings suggest a complementary role of these two ascertainment methods for Lynch syndrome.PMID:37879520 | DOI:10.1016/j.cgh.2023.10.005

Source: Clinical Colorectal Cancer - October 25, 2023 Category: Cancer & Oncology Authors: Heidi Rothenmund Lambert Pascal Deirdre Khan Christina Kim Bhavya Sharma Kim Serfas Bernard Chodirker Harminder Singh Source Type: research