Genetic Polymorphisms of UDP-Glucuronosyltransferases and Susceptibility to Antituberculosis Drug-Induced Liver Injury: A Systematic Review and Meta-Analysis

CONCLUSIONS: The polymorphisms of UGT1A1 rs3755319, UGT2B7 rs7662029, and UGT2B7 rs7439366 were significantly associated with AT-DILI susceptibility. However, this conclusion should be interpreted with caution due to the low number of studies and the relatively small sample size.PMID:37868740 | PMC:PMC10586897 | DOI:10.1155/2023/5044451

Source: Journal of Tropical Medicine - October 23, 2023 Category: Tropical Medicine Authors: Xinyu Chen Zhuolu Hao Nannan Wang Jia Zhu Honggang Yi Shaowen Tang Source Type: research