Phenotype and disease course differences in monogenic and sporadic childhood lupus

CONCLUSION: Patients with monogenic lupus are likely to have an early disease onset and a strong family history of lupus, as well as a guarded prognosis, which is likely due to the disease's severity and frequent infections. These differences may be related to the high consanguinity rate and underlying genetic variants.PMID:37878993 | DOI:10.1177/09612033231211065

Source: Lupus - October 25, 2023 Category: Rheumatology Authors: Sulaiman M Al-Mayouf Fatima Alkhars Alhanouf AlSaleem Source Type: research