Proteomics, Transcriptomics, and Phosphoproteomics Reveal the Mechanism of Talaroconvolutin-A Suppressing Bladder Cancer via Blocking Cell Cycle and Triggering Ferroptosis

This study revealed that TalaA inhibited bladder cancer mainly by arresting cell cycle to suppress proliferation and triggering ferroptosis to cause cell death. Conclusively, TalaA would be a potential candidate for treating bladder cancer by targeting MAPKs, suppressing the cell cycle, and inducing ferroptosis.PMID:37866481 | DOI:10.1016/j.mcpro.2023.100672
Source: Molecular and Cellular Proteomics : MCP - Category: Molecular Biology Authors: Source Type: research