Epigenetic regulation of 15-lipoxygenase-1 expression in human chondrocytes by promoter methylation

ConclusionThe expression level of 15-LOX-1 was elevated in OA cartilage, which may be part of a repair process. The upregulation of 15-LOX-1 in OA cartilage was not associated with the methylation status of its promoter, suggesting that other mechanisms are involved in its upregulation.
Source: Inflammation Research - Category: Research Source Type: research